Acute graft-versus-host disease, invasive aspergillosis and Clostridium difficile colitis after peripheral blood stem cell transplantation: A complex network of causalities and a challenge for prevention

Khanafer Nagham, Neuraz Antoine, Bénet Thomas, Cour Martin, Persat Florence, Labussière Hélène, Argaud Laurent, Michallet Mauricette, Vanhems Philippe

Graft-versus-host disease (GVHD) is a known risk factor for invasive aspergillosis (IA), but remains poorly studied in relation to Clostridium difficile infection (CDI). We report a case of a 58-years-old patient who developed an IA within a protected room, CDI and GVHD after allogeneic allogeneic peripheral blood stem cell transplantation (PBSCT). Factors associated with this complex condition in patients receiving allogeneic PBSCT need to be identified.

2015. Anaerobe; 33():98-100
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